I 1 -Imidazoline Agonist Moxonidine Decreases Sympathetic Nerve Activity and Blood Pressure in Hypertensives
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چکیده
منابع مشابه
I1-imidazoline agonist moxonidine decreases sympathetic nerve activity and blood pressure in hypertensives.
Moxonidine is an I1-imidazoline receptor agonist that reduces blood pressure in hypertensives. Experimental data suggest that moxonidine inhibits central sympathetic activity. However, whether such a mechanism is involved in vivo in humans is still unclear. We investigated the effects of 0.4 mg moxonidine orally on muscle sympathetic nerve activity and heart rate in an open study in 8 healthy v...
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We were approached by a 54-year-old female patient wishing to receive deep brain stimulation (DBS), a procedure that we previously discovered to normalize blood pressure (BP) in a drug-resistant hypertensive patient, to treat her severe, refractory hypertension. On her first visit to the specialist Hypertension Clinic (Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust) ...
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BACKGROUND Neurovascular compression of the rostral ventrolateral medulla, a major center regulating sympathetic nerve activity, may be causally related to essential hypertension. Microvascular decompression of the rostral ventrolateral medulla decreases elevated blood pressure. CASE DESCRIPTION A 47-year-old male essential hypertension patient with hemifacial nerve spasms exhibited neurovasc...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1998
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.32.6.1022